M. Cleat Szczepaniak

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In 2002-2003, the American College of Medical Informatics (ACMI) undertook a study of the future of informatics training. This project capitalized on the rapidly expanding interest in the role of computation in basic biological research, well characterized in the National Institutes of Health (NIH) Biomedical Information Science and Technology Initiative(More)
to provide therapeutics for the treatment of CD38-positive hematological malignancies. Introduction of the antibody against CD38 may, however, raise concerns of side effects such as an infusion reaction and pharmacological phenomena associated with the long half-life of the antibody. Although antibodies against CD38 have been administered to patients with(More)
BACKGROUND The aim of the study was to assess idiopathic nephrotic syndrome (INS) relapse rate, co-morbidities, and social status of adults diagnosed with INS in childhood. MATERIAL AND METHODS A written questionnaire was sent to 118 adults treated for INS in childhood. In 61 (51.7%) responders (aged 26.0 ± 6.2 years, range 18 - 51.5 years), we used(More)
Primary ciliary dyskinesia (PCD) is a rare (prevalence 1/ 20,000) genetic disease affecting motile cilia in the respiratory epithelium, spermatozoid flagella and primary cilia in the embryonic node. The most frequent (~60-70%) structural defect identified by TEM in the cilia of PCD patients are abnormal dynein arms. Several genes can cause PCD, but the(More)
An attempt has been made to further assess which fraction of bile can be stimulated by the main gastrointestinal hormones in rats. In the cannulated conscious animals the i.v. infusions of glucagon, impure Boots secretin, impure Boots cholecystokinin (CCK) and OP-CCK resulted in 8.9% (N.S.), 68.5% (P < 0.001), 88.7% (P < 0.001) and 19.0% (P < 0.05) increase(More)
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