M. Cicalese

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Hematopoietic stem/progenitor cells (HSPCs) are capable of supporting the lifelong production of blood cells exerting a wide spectrum of functions. Lentiviral vector HSPC gene therapy generates a human hematopoietic system stably marked at the clonal level by vector integration sites (ISs). Using IS analysis, we longitudinally tracked >89,000 clones from 15(More)
We consider a variational model for two interacting species (or phases), subject to cross and self attractive forces. We show existence and several qualitative properties of minimizers. Depending on the strengths of the forces, different behaviors are possible: phase mixing or phase separation with nested or disjoint phases. In the case of Coulomb(More)
We establish a pointwise comparison result for a nonlinear degenerate elliptic Dirichlet problem using an isoperimetric inequality involving the total mean curvature. In particular this result provides a sharp estimate for the extinction time of a class of compact surfaces, wider than the convex one, moving by mean curvature flow. Finally we present(More)
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