M. C. Reymond

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OBJECTIVE Recurrent ovarian, fallopian or peritoneal cancer with peritoneal carcinomatosis (ROCPC) is resistant to systemic chemotherapy. We assessed the safety and activity of laparoscopic pressurized intraperitoneal aerosol chemotherapy (PIPAC) in women with this cancer. METHODS In this open-label, single-arm phase 2 study, patients underwent 3 courses(More)
OBJECTIVE To assess the activity of laparoscopic Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) in women with recurrent, platinum-resistant ovarian cancer. METHODS Prospective case series using repeated courses q 28-42 days of PIPAC containing cisplatin 7.5 mg/m(2) and doxorubicin 1.5 mg/m(2) at 12 mmHg and 37°C for 30 min. Objective tumor(More)
Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a novel technique of intraperitoneal chemotherapy. First results obtained with PIPAC in patients with advanced peritoneal metastasis (PM) from gastric cancer (GC) are presented. Retrospective analysis: Sixty PIPAC were applied in 24 consecutive patients with PM from GC. 67 % patients had previous(More)
Based on biomedical literature databases, we tried a first step for constructing a gene expression "data warehouse" specific to human colorectal cancer (CRC). Results of genome-wide transcriptomic research were available from 12 studies, using various technologies, namely, SAGE, cDNA and oligonucleotide arrays, and adaptor-tagged amplification. Three(More)
Heightened awareness of the possible presence of gallbladder cancer (GBC) and the knowledge of appropriate management are important for surgeons practising laparoscopic cholecystectomy (LC). Long-term effects of initial LC versus open cholecystectomy (OC) on the prognosis of patients with GBC remain undefined. Patients who are suspected to have GBC should(More)
BACKGROUND Octogenarians with ovarian cancer limited to the abdomen may not be willing or able to undergo systemic chemotherapy. Low-dose pressurized intraperitoneal aerosol chemotherapy (PIPAC) with cisplatin and doxorubicin is a form of intra-abdominal chemotherapy which can be applied repeatedly and potentially prevents from the systemic side-effects of(More)
'Service d'Oncologie, Centre Hospitalier Universitaire Vaudois (CHUV), 1011 Lausanne, Switzerland; 2Laboratory of Clinical Pharmacology and Breast Evaluation Centre, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA; 3Institut de Medecine sociale et pre'ventive, Universite de Lausanne; 4Laboratoire de biochimie clinique, CHUV,(More)
•This is the first report of pressurized intraperitoneal aerosol chemotherapy (PIPAC) in a woman with pseudomyxoma peritonei.•PIPAC achieved clinical and histological disease remission.•PIPAC with cisplatin and doxorubicin may be effective in pseudomyxoma peritonei.
Die Arbeit der Musiker eines Symphonieorchesters wurde nach arbeitsphysiologischen, psychologischen und soziologischen Gesichtspunkten untersucht. Die Ergebnisse einer umfassenden Befragung von 113 Orchestermitgliedern werden mitgeteilt. Obwohl die Arbeitszeit mit 34 bis 36 Wochenstunden kürzer ist als in anderen Berufen, rechtfertigt es die(More)