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Methotrexate pharmacokinetics and prognosis in osteosarcoma.
- N. Graf, K. Winkler, M. Betlemovic, N. Fuchs, U. Bode
- Journal of clinical oncology : official journal…
- 1 July 1994
PURPOSE The influence of methotrexate (MTX) pharmacokinetic parameters on the efficacy of high-dose MTX (HDMTX) in osteosarcoma was analyzed. PATIENTS AND METHODS MTX serum peak values from 198… Expand