M. Begoña García-Cenador

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Chromosomal translocations involving the MALT1 gene are hallmarks of mucosa-associated lymphoid tissue (MALT) lymphoma. To date, targeting these translocations to mouse B cells has failed to reproduce human disease. Here, we induced MALT1 expression in mouse Sca1(+)Lin(-) hematopoietic stem/progenitor cells, which showed NF-κB activation and early lymphoid(More)
UNLABELLED Earlier in the past century, infections were regarded as the most likely cause of childhood B-cell precursor acute lymphoblastic leukemia (pB-ALL). However, there is a lack of relevant biologic evidence supporting this hypothesis. We present in vivo genetic evidence mechanistically connecting inherited susceptibility to pB-ALL and postnatal(More)
OBJECTIVES To analyze the short and long term results of tapes of different materials used to treat stress urinary incontinence (SUI). A secondary objective was to evaluate the ability to adjust the tape after implantation. MATERIALS AND METHODS Retrospective chart review of 355 patients with SUI operated between March 2003 and October 2011. Eight(More)
The latest studies of the interactions between oncogenes and its target cell have shown that certain oncogenes may act as passengers to reprogram tissue-specific stem/progenitor cell into a malignant cancer stem cell state. In this study, we show that the genetic background influences this tumoral stem cell reprogramming capacity of the oncogenes using as a(More)
<b>1.</b> The Information and Communication Technologies (ICTs) are the revolution of the XXI century, which allows doctors to be in immediate contact with the international scientific community, providing common professional projects and reviewing specific health situations, without intermediaries. However, studies specifically analyze the scope this type(More)
<b>1.</b> The extraordinary development of the new Information and Communication Technologies (ICTs) and their influence in our daily activity is obvious. Though, studies are needed to analyze in a specific way how these advantages affect daily activity of the occupational medicals, about the attitude and knowledge of the patients or even about the(More)
OBJECTIVE To compare the clinical impact of a prophylactic treatment with sublingual immunostimulation in the prevention of recurrent urinary tract infections (rUTIs) with the use of antibiotics. MATERIAL AND METHODS Retrospective cohort study evaluating the medical records of 669 women with rUTIs; 339 had a 6-month prophylaxis with antibiotics and 360 a(More)
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