M B Zariwala

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The effect of betel leaf extract and some of its constituents, eugenol, hydroxychavicol, beta-carotene and alpha-tocopherol, on benzo[a]pyrene-induced forestomach neoplasia in male Swiss mice was examined. Betel leaf and its constituents decreased the number of papillomas per animal with the maximum protection, considering molar dosage, exhibited by(More)
Epidemiological studies reveal that alcohol consumption is a risk factor for the cancer of the mouth, larynx, esophagus and various other organs. Of the various alcoholic beverages consumed in India, country liquors are widely consumed and that too by the economically weak section of the society. The present paper describes the experiments designed to(More)
The levels of some important drug activating and detoxyfying enzymes were estimated in the livers of Swiss mice treated with a local brand of country liquor. Following liquor ingestion in male mice elevated levels of hepatic cytochrome P-450 were observed, while female mice did not show this. Cytochrome b5 levels remained unchanged. Similarly in male mice,(More)
Different commercial brands of country liquors from three states of India (Maharashtra, Andhra Pradesh and Bihar) were tested in the Ames test using bacterial strains S. typhimurium TA 98 and TA 100 with and without metabolic activation. The commercial brands tested from Andhra Pradesh were nonmutagenic while those from Maharashtra and Bihar were mutagenic(More)
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