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WT1126 (RMFPNAPYL) is a human leukocyte antigen-A2 (HLA-A2)-restricted peptide derived from Wilms tumor protein 1 (WT1), which is widely expressed in a broad spectrum of leukemias, lymphomas and solid tumors. A novel T-cell-receptor (TCR)-like single-chain variable fragment (scFv) antibody specific for the T-cell epitope consisting of the WT1/HLA-A2 complex(More)
In two patients presenting with haemetemesis a diagnosis of isolated splenic vein occlusion (SVO) was established at laparotomy. SVO was caused by a pseudocyst of the pancreas in one case and a hydatid cyst of the left kidney in the other. A splenectomy plus distal pancreatectomy was done in the first case and cyst excision with ligation of the gastric(More)
Donor-derived Strongyloides stercoralis infections in transplant recipients are a rare but recognized complication. In this case series, we report donor-derived allograft transmission of Strongyloides in three solid organ transplant recipients. Following detection of infection in heart and kidney-pancreas recipients at two different transplant centers, a(More)
The aim of the study was to describe indications and complications of external ventricular drain (EVD) placement in children aged between 1 month and 16 years. This retrospective chart review was conducted at the Aga Khan University Hospital, Karachi, and comprised all children who underwent EVD placement from January 2007 to December 2014. Of the 177(More)
Pattern of admissions in a general surgical unit was studied from January 1980 to July 1981. Of 1021 cases admitted 697 were non-emergency and 324 were emergency admissions. Trauma and Appendicitis were the most common surgical emergencies, whereas Hernias, Anorectal conditions and diseases of the Gall bladder were the most frequent non-emergency(More)
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