M. A. Ushakova

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Data on specific antibodies to the bacterial antigens of Yersinia enterocolitica (serovars 03, 09) and Proteus mirabilis in rheumatoid arthritis (RA) patients are presented. According to the data of some researchers, these organisms play some role in the pathogenesis of RA. The highest level of IgG antibodies to Y. enterocolitica antigens of both serovars(More)
The new kit of reagents in format of the immunochip "ImmunoChip Borreliosis" for multiplex serologic analysis of mite-borne borreliosis demonstrated high diagnostic sensitivity and specificity. The percentage of detection of specific immunoglobulins was higher in "ImmunoChip Borreliosis" as compared with screening results in immune enzyme analysis. The high(More)
Articular lesions in 157 patients infected with ixodes tick-borne borreliosis (ITB) in a central Russia's region set on, on the average, in 4 months after tick attack; they were associated with systemic signs of an early disseminated infection and set on less seldom in a late period. The most often encountered systemic signs were as follows: secondary(More)
We used instrumental methods to characterise Lyme arthropathy in 79 patients with joint involvement and history of Lyme borreliosis. All of them had arthralgia and 45 of them also had arthritis. Radiological examination has established subchondral bone sclerosis in sacroiliac joints in 68% and sacroiliitis in 29% of the examinees. Scintigraphy revealed(More)
Analysis of the health status of about 3 thousand 15-year-old schoolchildren from the Central Administrative District of Moscow, made during annual prophylactic medical examinations during 1994 to 2003, revealed a clear tendency for diminished functional capacities in schoolchildren. There was a less than 30% reduction in the number of apparently healthy(More)
88 Mutations at the gene apterous ( ap ) encoding the transcriptional factor of Drosophila melanogaster lead to disturbances in the histolysis of the larval fat body, abnormal development of wings and some embryonic muscles, termination of vitellogenesis, and aberrant sex behavior [1–6]. Because it is known that all these traits are completely or partly(More)
Indirect immunofluorescence (II), enzyme-labelled antibodies (ELA), immune blotting (IB) were used for serological evaluation of 74 patients with Lyme disease living in the North-West and Central regions of Russia. Both acute and chronic borreliosis can be seropositive or seronegative. As shown by II and ELA, these patients had a moderate humoral response,(More)
58 Insect diseases caused by various pathogens are usually accompanied by marked changes in the duration of development, disturbances in metamorphosis, and decrease in fecundity, which indirectly indicate hormonal disturbances taking place during pathogenesis. Studies of the effect of various types of infections on different components of the hormonal(More)
Locomotor system has been studied in 24 patients with a history of Lyme's disease. All of them had arthralgia, 11 had relapsing arthritis, chronic arthritis occurred in 6 examinees. Arthritis presented as recurrent asymmetric mono-oligoarthritis affecting primarily joints of the lower limbs. Periarticular disorders were detected in 12 patients.(More)
School myopia is a most common health problem in schoolchildren, in adolescents in particular. School myopia resulted from connective tissue failure of the whole organism. Some data, such as the association of school myopia with the HLA system confirm this idea. New investigations in this direction will assist in concretizing the real cause of this type of(More)