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How do drugs of abuse modify neural circuitry and thereby lead to addictive behaviour? As for many forms of experience-dependent plasticity, modifications in glutamatergic synaptic transmission have been suggested to be particularly important. Evidence of such changes in response to in vivo administration of drugs of abuse is lacking, however. Here we show(More)
SCP001 Phasic nociceptive responses in dorsal raphe serotonin neurons JV Schweimer, DI Brierley, MA Ungless Imperial College London, London, UK; MRC Clinical Sciences Centre, London, UK Serotonin neurons play a central role in a variety of behavioural and cognitive functions, particularly in processing aversive stimuli. It has been suggested that(More)
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