M. A. Mañanas

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The purpose of this work is to evaluate characteristics of a respiratory model, RS1, in the presence of the following stimuli: exercise, hypercapnia and hypoxia. RS1 has a controller where the driving signal optimizes alveolar ventilation and respiratory frequency to minimize the respiratory work output. A comparative study of the steadystate and transient(More)
Quantitative electroencephalographic (EEG) analysis is very useful for diagnosing dysfunctional neural states and for evaluating drug effects on the brain, among others. However, the bidirectional contamination between electrooculographic (EOG) and cerebral activities can mislead and induce wrong conclusions from EEG recordings. Different methods for ocular(More)
Work-related upper extremity disorders as epycondylitis and tendonitis are closely related to localized muscle fatigue of extensor forearm muscles. The aim of this work is to evaluate levels of activity, fatigue and interactions between the main extensor muscles of the wrist. Surface EMG signals were acquired from extensor carpi radialis (ECR), extensor(More)
Electroencephalographic artifacts associated with eye movements are a potential source of error in the EEG analysis when its interpretation is performed for evaluating the influence of drugs and the diagnosis of neurological disorders. In this study, a new automatic method for artifact filtering based on independent component analysis (ICA) is proposed.(More)
Quantitative analysis of electroencephalographic signals (EEG) and their interpretation constitute a helpful tool in the assessment of the bioavailability of psychoactive drugs in the brain. Furthermore, psychotropic drug groups have typical signatures which relate biochemical mechanisms with specific EEG changes. To analyze the pharmacological effect of a(More)
Analysis of the EEG by means of spectral parameters permit to evaluate the influence of a drug and to diagnose dysfunctional states in neurology, psychiatry and psychopharmacology. Eye movement artifacts contaminate EEG signals and can produce errors in this analysis. Regression based technique is considered the 'gold standard' artifact removal procedure(More)
The Poincare plots-a simple graphical, nonlinear method was implemented to express 24-h QT interval changes. The group of 23 pts with hypertrophic cardiomyopathy was analyzed (11 pts. with higher and 12 with lower risk of sudden cardiac death). The control group consisted of 10 healthy subjects. 24-h Holter ECG recordings were analyzed and RR and QT(More)
Understanding the respiratory control system and the ventilatory pattern under hypercapnic stimulus is important to interpret the acute exacerbation of COPD and the condition of patients connected to mechanical ventilation. The purpose of this study is the analysis of respiratory and muscle parameters in order to obtain the most sensitive and characteristic(More)