The effect of the CSF components of the rats who had restored motor deficiency after left unilateral removal of motor neocortex, was studied in the rats with an analogous brain lesion. The first group of animals received a thermostable fraction of the donor CSF containing active factors of the posture asymmetry (FPA). The second group of animals were given… (More)
Reaction of pose asymmetry was studied in rats subjected to unavoidable pain stimulation of 5 and 20 min duration after chordotomy. Single 20-min stimulation led to the appearance in all animals of right-side pose asymmetry, if the chordotomy took place immediately after the impact. If the chordotomy took place 24 h after the stimulation, the animals were… (More)
The disappearance of posture asymmetry factor activity in the CSF after three weeks of unilateral removals of the neocortex motor region is caused by inactivation factors (IF), which are thermolabile proteins with m.v. about 80 kD and 150 kD. One of IF (150 kD) interacted with protein A which shows its immunoglobulin++ nature.
The role of neurohumoral factors in the mechanisms of restoring the lost motor functions after two successive unilateral removals of the neocortex motor region, was studied. The dynamics of the restoring correlated with the posture asymmetry factor (PAF) activity in the CSF. PAF activity was reduced during the restoring by an inactivation factor (FI).… (More)
The motor function recovery was studied for 3 weeks after surgical unilateral damage of the motor cortex in albino rats. Distance between the 1st and the 5th fingers was compared in intact sham--operated, operated rats, and operated animals which were suboccipitally injected with brain extract obtained from reconvalescent donor rats with the same type of… (More)
The peptide nature of the posture asymmetry factor (PAF) produced in the brain after unilateral removal of the motor region of the neocortex was established. The inactivation of PAF activity in the brain toward the end of the third week after the removal is due to PAF inactivation by the endogenous factor absent from the intact brain. The molecular weight… (More)