M. A. Dambacher

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Objective: To evaluate the loss of trabecular and cortical bone mineral density in radius, ulna and tibia of spinal cord injured persons with different levels of neurologic lesion after 6, 12 and 24 months of spinal cord injury (SCI).Design: Prospective study in a Paraplegic Centre of the University Hospital Balgrist, Zurich.Subjects and methods:(More)
OBJECTIVE To evaluate the effectiveness of an early intervention program for attenuating bone mineral density loss after acute spinal cord injury (SCI) and to estimate the usefulness of a multimodality approach in diagnosing osteoporosis in SCI. DESIGN A single-case, experimental, multiple-baseline design. SETTING An SCI center in a university hospital.(More)
Design:A prospective inception cohort study with an observational analytic design in a spinal cord injury (SCI) centre hospital.Objective:To assess changes in trabecular and compact bone of the tibia and radius prospectively in subjects with SCI.Subjects:In total, 10 individuals with an acute SCI.Methods:Trabecular and compact bone density of the tibia and(More)
INTRODUCTION Quantitative bone assessment today is primarily based on the analysis of bone mineral density (BMD). The geometric and structural properties of bone, which are important parameters for skeletal strength, are generally not considered in the routine clinical assessment of spinal cord injury-related osteopenia. OBJECTIVE To study changes in(More)
PURPOSE To evaluate if osteonecrosis diagnosed on MR images of the knee relates to reduced bone mineral density (BMD) and may be caused by an insufficiency fracture. MATERIAL AND METHODS Thirty-two consecutive patients (8 men, 24 women; age range 27-82 years, mean 62 years) with MR findings of osteonecrosis of the femoral or tibial condyle were(More)
Aspects of Calcitonin-Research 1. Calcitonin an antagonist of parathyroid hormone, has been expected to be of importance in the treatment of metabolic bone disease. Available data indicate that the serum calcium in hypercalcemia and high bone turnover conditions can be lowered, although to a limited extent. In Paget's disease of the bone, the osteoclastic(More)
In 1972, Harris et al. (1) reported a marked increase of cortical bone formation and calcium accretion in adult dogs treated with high doses of growth hormone. Since in osteoporosis, bone formation is insufficient to compensate for the bone loss, human growth hormone (HGH) appears to be a promising substance for the treatment of this bone condition. Thus, a(More)
1. Hypo- and hypercalcemia can be explained as derangements of the calcium homeostasis. Hypocalcemic tetany usually alarming the patient tremendously is, at least in adults, rarely life-threatening. Hypercalcemia leads in 30% of the cases to clinical symptoms which may inadvertedly pass into a state of hypercalcemic crisis. This latter requires an often(More)
Die interessante Arbeit von ZUhlke et al. veranla6t uns zu einigen, fiir den diagnostischen und therapeutischen Alltag vielleicht nUtzlichen Kommentaren. 1. Der Steilenwert der aufwendigen Bestimmung des ionisierten Calciums ist fur uns nicht so augenffillig Ffille mit Normocalcifimie, aber erh6htem ionisiertem Calcium sind nach unserer Erfahrung extreme(More)