Mônica Conchon

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Approximately 20–30% of cases of adult ALL are Philadelphia chromosome positive (Phþ ). Owing to the dismal outcome of Phþ ALL with chemotherapy, allogeneic hematopoietic SCT (HSCT) is routinely offered as it is considered to be the only potentially curative therapy. The usual therapeutic intervention in patients with ALL relapsing after allogeneic HSCT is(More)
Description of the evidence collection method These guidelines were drafted after the preparation of 19 questions relevant to the diagnosis and treatment of chronic myeloid leukemia. The questions were structured using the PICO (Patient‐Intervention‐Comparison‐Outcome) methodology, thus enabling the creation of strategies to search for evidence (Appendix 1)(More)
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