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Fast onset and high-level neurospecific transgene expression in vivo is of importance for many areas in neuroscience, from basic to translational, and can significantly reduce the amount of vector load required to maintain transgene expression in vivo. In this study, we tested various cis elements to optimize transgene expression at transcriptional,… (More)
A cytomatrix of proteins at the presynaptic active zone (CAZ) controls the strength and speed of neurotransmitter release at synapses in response to action potentials. However, the functional role of many CAZ proteins and their respective isoforms remains unresolved. Here, we demonstrate that presynaptic deletion of the two G protein-coupled receptor… (More)
2008: PhD Thesis: " Factores intravesiculares que modulan la exocitosis. Implicaciones farmacológicas " (Intravesicular factors that modulate the exocytosis. Pharmacological implications), under direction of Dr.