Mónica Hernández Alava

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BACKGROUND Analysts frequently estimate health state utility values from other outcomes. Utility values like EQ-5D have characteristics that make standard statistical methods inappropriate. We have developed a bespoke, mixture model approach to directly estimate EQ-5D. An indirect method, "response mapping," first estimates the level on each of the 5(More)
OBJECTIVE This study aims to provide robust estimates of EQ-5D as a function of the HAQ and pain in patients with RA. METHOD Repeated observations were made of patients diagnosed with RA in a US observational cohort (n = 100 398 observations) who provided data on HAQ, pain on a visual analogue scale and the EQ-5D questionnaire. We used a bespoke(More)
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