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Inflammation is known to be necessary for promoting, sustaining, and tuning CD8+ T cell responses. Following experimental Leishmania donovani infection, the inflammatory response is mainly induced by the transcription factor IRF-5. IRF-5 is responsible for the activation of several genes encoding key pro-inflammatory cytokines, such as IL-6 and TNF. Here,(More)
  • M Smans
  • 1989
While cancer maps are a convenient way of conveying quickly such information as the presence of clusters of areas at high or low risk, the level of statistical significance of these occurrences cannot be easily derived. A method of measuring the "spatial aggregation," based on rank, was presented in the Atlas of Cancer in Scotland (Kemp et al. 1985) and(More)
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