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When presented with an auditory sequence, the brain acts as a predictive-coding device that extracts regularities in the transition probabilities between sounds and detects unexpected deviations from these regularities. Does such prediction require conscious vigilance, or does it continue to unfold automatically in the sleeping brain? The mismatch(More)
Sir, We read with interest the article by Tzovara et al. (2015), recently published in Brain. In this study the authors adapted a paradigm we previously designed (Bekinschtein et al., 2009) to probe the EEG of comatose patients in response to two types of violations of auditory regularities. Unfortunately, several important problems mitigate the reliability(More)
BACKGROUND It is well recognized that sleep is severely disturbed in patients in intensive care units (ICU) and that this can compromise their rehabilitation potential. However, it is still difficult to objectively assess sleep quantity and quality and the determinants of sleep disturbance remain unclear. The aim of this study was therefore to evaluate(More)
During visual perception, automatic bottom-up and controlled top-down processes occur simultaneously and interact in a complex way, making them difficult to isolate and characterize. In rare neurological conditions, such a dissociation can be achieved more easily. In the present work, we studied a patient (AC) with a posterior lesion of the corpus callosum(More)
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