Mário Sérgio Oliveira Swerts

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UNLABELLED Cleft lip and/or palate represent the most common congenital anomaly of the face. AIM To describe the correlation between non-syndromic cleft lip and/or palate and gender, and its severity in the Brazilian population. METHODS Cross-sectional study, between 2009 and 2011, in a sample of 366 patients. The data was analyzed with descriptive(More)
BACKGROUND AND OBJECTIVE Nonsyndromic cleft lip and/or palate (NSCL/P) is a complex disease associated with both genetic and environmental factors. One strategy for identifying of possible NSCL/P genetic causes is to evaluate polymorphic variants in genes involved in the craniofacial development. DESIGN We carried out a case-control analysis of 13 single(More)
Objective : Many studies have demonstrated a high frequency of dental anomalies in patients with cleft lip and/or palate. Because dental anomalies may complicate dental treatment, we investigated the prevalence of dental anomalies in a group of Brazilian patients with nonsyndromic cleft lip and/or palate. Design, Participants, Setting : Retrospective(More)
Polymorphisms at Regions 1p22.1 (rs560426) and 8q24 (rs1530300) Are Risk Markers for Nonsyndromic Cleft Lip and/or Palate in the Brazilian Population Elizabete Bagordakis, L ıvia M aris Ribeiro Paranaiba, Luciano Abreu Brito, Sibele Nascimento de Aquino, Ana Camila Messetti, Herc ılio Martelli-Junior, Mario Sergio Oliveira Swerts, Edgard Graner, Maria Rita(More)
The aim of this study was to evaluate the influence of the γ-aminobutyric acid receptor type A β-3 subunit (GABRB3) polymorphisms in patients with nonsyndromic cleft lip and/or palate (NSCL/P). We carried out a structured case-control analysis of three GABRB3 polymorphisms (rs4477673, rs6576618, and rs981778) in 229 patients with nonsyndromic cleft lip with(More)
OBJECTIVE To investigate the distribution of several types of clefts among adolescents and adults receiving treatment at the Center for Rehabilitation of Craniofacial Anomalies, Unifenas, Minas Gerais State, Brazil. METHODS AND MATERIALS A total 154 untreated patients of low socioeconomic means with cleft lips and/or palates, without additional(More)
OBJECTIVE This report describes the clinical and genetic features of two large and unrelated families with Van der Woude syndrome in Brazil, emphasizing the range of anomalies found within and between the families. PATIENTS Family 1 included 54 descendants spanning five generations, with 12 (22.23%) individuals manifesting Van der Woude syndrome. In(More)
Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is the most common orofacial birth defect with a wide range prevalence among different populations. Previous association studies with populations from Europe and Asia have identified putative susceptibility markers for NSCL/P in fibroblast growth factor 12 (FGF12), vinculin (VCL), connexin 43(More)
Hypohidrotic ectodermal dysplasia (HED) is a type of genodermatosis characterized by the abnormal development of sweat glands, teeth, and hair. The most prevalent form of HED is X-linked hypohidrotic ectodermal dysplasia (XLHED), which is associated with mutations in the EDA gene. The aim of this case report was to describe a family with XLHED with emphasis(More)
INTRODUCTION Cleft lip and/or palate (CL/P) represent the most common congenital anomalies of the face. OBJECTIVE To evaluate the prevalence of depressive symptoms in children and adolescents with nonsyndromic cleft lip and/or palate (nsCL/P). METHODS We conducted an observational, case-control study, with a case study group composed of 61 patients with(More)