Mário Jorge Amorim

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Using domestic pigs as an animal model, we here validated a reproducible and standardized myocardial infarction (MI) surgical model, to achieve the largest possible infarct extent with the lowest morbidity and mortality. To this end, we included several anesthetic and perisurgical precautions to minimize surgical complications. Mortality and morbidity(More)
In animal experiments, elevating systolic pressures induces diastolic dysfunction and may contribute to congestion, a finding not yet translated to humans. Coronary surgery patients (63 ± 8 years) were studied with left ventricular (LV) pressure (n = 17) or pressure-volume (n = 3) catheters, immediately before cardiopulmonary bypass. Single-beat graded(More)
The first Cox-maze procedure was performed in 1987, demonstrating the feasibility of a non-pharmacological treatment for atrial fibrillation (AF). Since then, surgery for AF has changed over time, in parallel with technological advances. Replacement of surgical incisions with linear ablation lines made a previously cumbersome procedure accessible to most(More)
OBJECTIVE To investigate the effects of left ventricular (LV) pressure overload and diabetes on the apelinergic system. RESEARCH DESIGN/METHODS Pressure overload was established in rats by supra-renal aortic-banding. Six weeks later, diabetes was induced by streptozotocin (65 mg/kg, intraperitoneal), resulting in four groups: sham, banded (BA), diabetic(More)
Surgical angioplasty of the left main coronary artery has been previously performed in a small number of centres. We present our initial experience with this surgical technique in three consecutive cases. There were no deaths or myocardial infarcts. One patient had a stroke. Surgical angioplasty of the left main coronary artery can be performed in a(More)
OBJECTIVES To compare the decrease in left ventricular mass index (LVMI) by magnetic resonance imaging (MRI) versus transthoracic echocardiography (TTE) after aortic valve replacement (AVR) for severe aortic stenosis with Epic and Epic Supra stented porcine bioprostheses (St Jude Medical, Inc, St Paul, Minn). METHODS This prospective multicenter study(More)
BACKGROUND Intraventricular pressure gradients have been described between the base and the apex of the left ventricle during early diastolic ventricular filling, as well as, their increase after systolic and diastolic function improvement. Although, systolic gradients have also been observed, data are lacking on their magnitude and modulation during(More)
The authors describe an acquired atrioventricular septal defect that has resulted from a blunt chest trauma. Besides being an uncommon traumatic heart injury, this case has the particularities of the non-involvement of other adjacent anatomical structures and the long delay between the accident and the occurrence of the myocardial rupture.
OBJECTIVES The aim of this study was to compare the results of concomitant unipolar radiofrequency ablation of nonparoxysmal atrial fibrillation (AF) between rheumatic and degenerative valve disease (RHD versus DVD). METHODS Between 2005 and 2012, 96 patients underwent AF ablation with unipolar radiofrequency concurrently with heart valve surgery. They(More)
OBJECTIVE To determine whether the Trifecta bioprosthetic aortic valve produces postoperative haemodynamic results comparable with or better than those of the Magna Ease aortic valve bioprosthesis. METHODS We retrospectively reviewed the medical records of patients who had undergone aortic valve replacement with Trifecta or Magna Ease prostheses at eight(More)