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  • Carla Manuela Crispim Nascimento, Jéssica Rodrigues Pereira, +6 authors Florindo Stella
  • Psychology, Medicine
  • Current Alzheimer research
  • 2014 (First Published: 11 September 2014)
  • The benefits of physical exercise to reduce low-grade inflammation and improve Brain-Derived Neurotrophic Factor (BDNF) levels and cognitive function became a growing field of interest. Low-gradeContinue Reading
  • Oscar Henrique Pereira Ramos, Alexandre Kauskot, +10 authors Arnaud Bonnefoy
  • Medicine
  • Clinical & experimental metastasis
  • 2008
  • The integrin alpha(v)beta(3) is involved in multiple aspects of malignant cancer, including tumor angiogenesis and metastasis, which makes the receptor a key target for the development of anti-cancerContinue Reading
  • Márcia Regina Cominetti, Cristina Helena Bruno Terruggi, +6 authors Heloisa S Selistre-de-Araújo
  • Biology, Medicine
  • The Journal of biological chemistry
  • 2004 (First Published: 30 April 2004)
  • Alternagin-C (ALT-C), a disintegrin-like protein purified from the venom of the Brazilian snake Bothrops alternatus, interacts with the major collagen I receptor, the alpha(2)beta(1) integrin,Continue Reading
  • James Almada da Silva, Amanda Blanque Becceneri, +5 authors Márcia Regina Cominetti
  • Chemistry, Medicine
  • Journal of chromatography. B, Analytical…
  • 2012 (First Published: 1 August 2012)
  • This study describes an optimization of [6]-, [8]- and [10]-gingerol isolation and purification in semi-preparative HPLC scale and their anti-proliferative activity. The gingerols purification wasContinue Reading
    Alternagin-C (ALT-C) is a disintegrin-like, Cys-rich protein isolated from Bothrops alternatus snake venom, which has been shown to induce in vivo angiogenesis. Therefore, this protein could beContinue Reading
  • Heloisa Sobreiro Selistre-de-Araújo, Márcia Regina Cominetti, +5 authors Verônica Morandi
  • Biology, Medicine
  • Brazilian journal of medical and biological…
  • 2005 (First Published: 1 October 2005)
  • The alpha2beta1 integrin is a major collagen receptor that plays an essential role in the adhesion of normal and tumor cells to the extracellular matrix. Alternagin-C (ALT-C), a disintegrin-likeContinue Reading
  • Oscar Henrique Pereira Ramos, Cristina Helena Bruno Terruggi, +6 authors Heloisa S Selistre-de-Araújo
  • Biology, Medicine
  • Archives of biochemistry and biophysics
  • 2007 (First Published: 1 May 2007)
  • We have previously demonstrated that alternagin-C (ALT-C), a disintegrin-like protein from the venom of the Brazilian snake Bothrops alternatus, induces human vascular endothelial cell (HUVEC)Continue Reading
    The alpha(5)beta(1) integrin is one of the major fibronectin receptors which plays an essential role in the adhesion of normal and tumor cells to extracellular matrix. Here, we describe the isolationContinue Reading
  • Julio Conceicao Filho, André Lúcio Franceschini Sarria, +7 authors Márcia Regina Cominetti
  • Biology, Medicine
  • PloS one
  • 2014 (First Published: 5 September 2014)
  • Cancer is the second leading cause of death worldwide and there is epidemiological evidence that demonstrates this tendency is emerging. Naringenin (NGEN) is a trihydroxyflavanone that shows variousContinue Reading