Lyle W. Horn

Learn More
1. The giant axon of Myxicola infundibulum was assessed for its suitability as a model preparation for study of amino acid transport mechanisms.2. The amino acid composition of axoplasm was measured and compared with those of coelomic fluid, muscle and axon sheath. The axoplasmic composition is unique. Axoplasm/coelomic fluid concentration ratios are all(More)
Effects of external K+ concentration, [K+]o, on K+ transport rate and on relative K+, an index of intracellular K+ concentration, were studied in adipocytes isolated from rat epididymal fat pads. 2. Relative K+ changed upon a step change of [K+]o from normal, but with continued exposure to the second [K+]o the relative K+ returned to or approached the(More)
  • L W Horn
  • The American journal of physiology
  • 1989
The transport of L-glutamate (Glu) by single muscle fibers of Balanus nubilus was studied by means of internal dialysis in an effort to obtain transport data under well-defined intracellular conditions. It is shown that the method effectively controls the sarcoplasmic amino acid composition and Glu metabolism. It was found that the classic neutral amino(More)
Lung surfactant might exchange reversibly between the alveolar gas-liquid interface and the liquid lining layer. This solubilization process could then contribute to time-dependent pulmonary mechanical phenomena. Theoretical analysis of a model alveolus shows how solubilization can produce recoil pressure relaxation of the lung. The analysis shows that for(More)
It is shown that the axoplasmic composition of acidic and neutral amino acids can be controlled effectively by the method of internal dialysis. Direct assay for specific binding and measurement of diffusion coefficients in axoplasm show that there is no significant binding or compartmentalization of amino acids. The dependence of amino acid efflux on(More)
  • L W Horn
  • The American journal of physiology
  • 1992
The dependence of L-glutamate influx on extracellular Na and L-glutamate concentrations was determined using internally dialyzed single muscle fibers of Balanus nubilus. Internal Na and glutamate concentrations were held at zero, and the cell membrane potential was constant. Flux activation curves for external glutamate were measured for five different(More)
  • 1