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OBJECTIVE To characterize the human ovarian xenograft revascularization process. DESIGN Prospective experimental study. SETTING Gynecology research unit in a university hospital. PATIENT(S) Ovarian biopsies were obtained from 12 women aged 22-35 years. INTERVENTION(S) Frozen-thawed human ovarian fragments were intraperitoneally grafted into nude(More)
BACKGROUND This study was designed to assess the impact of different ovarian tissue transplantation sites on the follicular pool and ovarian tissue integrity after short-term grafting, since there is no consensus in the literature as to the optimal grafting site in experimental models. METHODS Frozen-thawed ovarian tissue from eight patients was grafted(More)
Cryobanking and transplantation of ovarian tissue is a promising approach to restore fertility in cancer patients. However, ischemic stress following avascular ovarian cortex grafting is known to induce stromal tissue fibrosis and alterations in follicular development. The aim of the study was to analyze the impact of freeze-thawing and grafting procedures(More)
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