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Exposure to hypercapnic hypoxia (asphyxia), but not hyperoxic hypercapnia, results in increased sympathetic activity that persists after exposure. To determine the contribution of CO2 to the post-hypoxia sympathoexcitation, we exposed 12 normal volunteers to hypocapnic and hypercapnic hypoxia (SaO2 approximately 85%) for 20 min each on different days. We(More)
This study was aimed at comparing the effect of unilateral hippocampal inactivation with tetrodotoxin (TTX) and lidocaine on spatial memory consolidation. Both drugs block voltage-dependent sodium channels. However, TTX and lidocaine differ in the duration of their effects, with maximum TTX effect between 30 min and 120 min, washing out in 24 hours.(More)
study the neural basis of behaviour, scientists apply different kinds of techniques. By using temporal inactivating methods, neuroscientists can control not only which brain structures are involved in certain behaviour, but also the temporal demands of TTX is a specific voltage-dependent sodium channel blocker whose maximum effect begins between 30 and 120(More)
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