Luying Wang

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The clinical application of dihydroartemisinin (DHA) has been hampered due to its poor water-solubility. To overcome this hurdle, we devised a novel polymer-drug conjugate, multiarm polyethylene glycol-dihydroartemisinin (PEG-DHA), made by linking DHA with multiarm polyethylene glycol. Herein, we investigated PEG-DHA on chemical structure, hydrolysis,(More)
Poor delivery of insoluble anticancer drugs has so far precluded their clinical application. In this study, an efficient tumor targeted-nanoparticle delivery system, transferrin-eight-arm-polyethylene glycol-dihydroartemisinin nanoparticles (TF-8arm-PEG-DHA NPs) for the vehiculation of dihydroartemisinin (DHA) was first prepared and evaluated for its(More)
The development of a novel non-sulfided catalyst with high activity for the hydrotreatment processing of plant oils, is of high interest as a way to improve the efficient production of renewable diesel. To attempt to develop such a catalyst, we first synthesized a high activity flower-like Ni-PTA catalyst used in the hydrotreatment processes of plant oils.(More)
The non-sulfided Ni-PTA/Al2O3 catalyst was developed to produce green diesel from the hydroprocessing of Jatropha oil. The Ni-PTA/Al2O3 catalyst was prepared by one-pot synthesis of Ni/Al2O3 with the co-precipitation method and then impregnanting Ni/Al2O3 with PTA solution. The catalysts were characterized with BET, SEM-EDX, TEM, XRD, XPS, TGA and NH3-TPD.(More)
Tremendous attentions have been attracted to the foods labeled with natural, green, organic, and nuisanceless conception of healthy diet. Therefore, it is of great significance to establish relative defining guidance for safe assessment of botanicals. Cyclocarya paliurus (Batal.) Iljinsk (family Cyclocaryaceae), called sweet tea tree, is a well-known edible(More)
Nickel oxide (NiO) and phosphotungstic acid (PTA) supported on a ZIF-8 (NiO-PTA/ZIF-8) catalyst was first synthesized and it showed high activity and good selectivity for the hydrocracking of Jatropha oil. The catalyst was characterized by SEM, SEM-EDS, TEM, N2 adsorption, FT-IR, XRD and XPS. Compared with the NiO-PTA/Al2O3 catalyst, the selectivity of(More)
An efficient and environmental-friendly extraction method has been developed for extraction of ursolic acid (UA) from Hedyotis diffusa by using subcritical water extraction (SWE). The experiments were carried out at different particle sizes (20–100 mesh), extraction temperature (120–200 • C), extraction time (10–50 min), solvent/solid ratio (20–40 mL/g),(More)
The combination of drug loaded micelles and hydrogel could overcome the limitations with the use of the individual components as drug carriers. Herein, novel injectable supramolecular hydrogels based on the inclusion complexation between α-cyclodextrin and the binary-drug loaded micelles which self-assembled from 8arm-polyethylene glycol-betulinic acid(More)
Smart thin hydrogel coatings are fabricated to capture and release targeted cancer cells by simultaneously tuning surface hydrophobicity and topography. At physiological temperature, the targeted cancer cells are captured on the hydrophobic and wrinkled coating surface. At room temperature, the captured cells are released from the hydrophilic and smooth(More)