Lung-Chih Lee

  • Citations Per Year
Learn More
The aims of this study were to investigate the prevalence of sleep disorders in patients with end-stage renal disease (ESRD), and to assess the effect of dialysis schedule on sleep quality and the presence of daytime symptoms. We prospectively selected 150 long-term hemodialysis (HD) patients in three groups (morning, afternoon, and evening dialysis) and(More)
BACKGROUND Oxidative stress is highly prevalent in hemodialysis patients and may contribute to atherosclerosis and mortality. The copy number of mitochondrial DNA (mtDNA) is affected by oxidative stress in blood circulation. This study aimed to test whether mtDNA copy number correlates with oxidative stress and predicts all-cause mortality in nondiabetic(More)
OBJECTIVE Both chronic inflammation and dysregulation of bone and mineral metabolism are closely related with long-term outcomes of dialysis patients. Our objective was to investigate the relationship between these two abnormalities. DESIGN This was a cross-sectional study. SETTING This study was performed at a hospital-based hemodialysis center. (More)
BACKGROUND/AIMS The influence of oxidative stress and peritoneal clearance on alterations in mitochondrial DNA (mtDNA) copy number in continuous ambulatory peritoneal dialysis (CAPD) patients was investigated. METHODS Ninety-one CAPD patients (age, 30-57 years) and 99 age-matched healthy subjects were enrolled. Biochemical variables, plasma(More)
Mitochondria (mt) are highly susceptible to reactive oxygen species (ROS). In this study, we investigated the association between a region within the displacement loop (D-loop) in mtDNA that is highly susceptible to ROS and oxidative stress markers in chronic dialysis patients. We enrolled 184 chronic dialysis patients and 213 age-matched healthy subjects(More)
Emphysematous pyelonephritis (EPN) is a severe and complicated renal infection characterized by gas formation within the infected kidney and its surrounding tissues. Early diagnosis with a high index of suspicion and aggressive treatment are important for improving outcome. Bilateral involvement is rare, and surgical intervention is usually required because(More)
Title: Lack of association between the mutations of the gene encoding mitochondrial D310 (displacement loop) mononucleotide repeat and oxidative stress in chronic dialysis patients in Taiwan
  • 1