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Is it good medical practice for physicians to " eyeball " a patient's race when assessing their medical status or even to ask them to identify their race? This question was captured in a 2005 episode of " House M.D., " Fox television's medical drama. In the episode, a black patient with heart disease refuses a hospital physician's prescription for what is(More)
The 2005 guidelines of the American Thoracic Society/European Respiratory Society recommend the use of race- and/or ethnic-specific reference standards for spirometry. Yet definitions of the key variables of race and ethnicity vary worldwide. The purpose of this study was to determine whether researchers defined race and/or ethnicity in studies of lung(More)
The fetal liver ¡sozymes aldolase A and pyruvate kinase K increase in livers of adult rats fed a choline deficient-diet contain ing 0.1% ethionine. Oval cells isolated by centrifugal elutriation from preneoplastic livers of animals receiving the carcinogenic diet contained these fetal forms as well as fetal-adult isozyme hybrids. In contrast, parenchymal(More)
Much of the recent debate over race, genetics, and health has focused on the extent to which typological notions of race have biological meaning. Less attention, however, has been paid to the assumptions about the nature of "populations" that both inform contemporary biological and medical research and that underlie the concept of race. Focusing(More)
  • Lundy Braun
  • 2015
Spirometry is the most common lung function test and represents the cornerstone diagnostic and management tool for individuals with chronic respiratory diseases. Variability and changing temporal trends in lung function measurements, however, have contributed to the problem of standardizing spirometry, especially with regard to 'race correction'. This(More)
We have established an in vivo/in vitro system in which epithelial cells ("oval cells") isolated from livers of rats fed a carcinogenic diet for a very brief period are placed in culture and transfected with an oncogene. Injection s.c. into nude mice of oval cells transfected with the activated r-I In-rav (EJ oncogene) produces tumors with morphological(More)
In rats maintained on a carcinogenic diet (choline deficient containing 0.1% ethionine), the levels of c-myc and p53 mRNAs increased by 4 wk after animals were placed on the diet. Cell isolation studies showed that the change in c-myc takes place in oval cells, while p53 increases predominantly in oval cells but also in hepatocytes. To determine whether(More)
Is it good medical practice for physicians to " eyeball " a patient's race when assessing their medical status or even to ask them to identify their race? This question was captured in a 2005 episode of " House M.D., " Fox television's medical drama. In the episode, a black patient with heart disease refuses a hospital physician's prescription for what is(More)
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