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Weathering the COVID-19 storm: Lessons from hematologic cytokine syndromes
Abstract A subset of patients with severe COVID-19 develop profound inflammation and multi-organ dysfunction consistent with a “Cytokine Storm Syndrome” (CSS). In this review we compare theExpand
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Hemophagocytic syndromes (HPSs) including hemophagocytic lymphohistiocytosis (HLH) in adults: A systematic scoping review.
Most knowledge of hemophagocytic syndromes (HPSs) including hemophagocytic lymphohistiocytosis (HLH) is derived from pediatric studies; literature on adult HPS/HLH predominantly consists of smallExpand
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Soluble interleukin-2 receptor is a sensitive diagnostic test in adult HLH.
Serum soluble interleukin-2 receptor (sIL-2r) is an important disease marker in hemophagocytic lymphohistiocytosis (HLH), but there are no published data on its diagnostic value in adults. WeExpand
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Clinical utility of soluble interleukin-2 receptor in hemophagocytic syndromes: a systematic scoping review
The serum-soluble interleukin-2 receptor (sIL-2r) level is considered an important diagnostic test and disease marker in hemophagocytic syndromes/hemophagocytic lymphohistiocytosis (HPS/HLH).Expand
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Recognizing IgG4-related tubulointerstitial nephritis
AbstractPurpose of the reviewImmunoglobulin G4-related disease (IgG4-RD) is a systemic fibroinflammatory disorder affecting nearly all organs, including the kidney. Tubulointerstitial nephritisExpand
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IgG4-related disease: what a hematologist needs to know
IgG4-related disease is a fibro-inflammatory condition that can affect nearly any organ system. Common presentations include major salivary and lacrimal gland enlargement, orbital disease, autoimmuneExpand
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Confronting the controversy: interleukin-6 and the COVID-19 cytokine storm syndrome
The concept of coronavirus disease 2019 (COVID-19)-related cytokine storm syndrome (COVID-CSS) emerged early in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic to explainExpand
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Dysmetabolic hyperferritinemia is associated with normal transferrin saturation, mild hepatic iron overload, and elevated hepcidin
Hyperferritinemia is common in individuals with the metabolic syndrome (dysmetabolic hyperferritinemia), but its pathophysiology and the degree to which it reflects tissue iron overload remainsExpand
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Amelioration of COVID‐19 related cytokine storm syndrome: Parallels to chimeric antigen receptor‐T cell cytokine release syndrome
Abstract Coronavirus disease‐2019 (COVID‐19) severity appears to parallel the host immune response, with a subset of patients developing COVID‐19 cytokine storm syndrome (CSS).(1) Serum inflammatoryExpand
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IgG4‐related disease and lymphocyte‐variant hypereosinophilic syndrome: A comparative case series
To compare the clinical and laboratory features of IgG4‐related disease (IgG4‐RD) and lymphocyte‐variant hypereosinophilic syndrome (L‐HES), two rare diseases that often present with lymphadenopathy,Expand
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