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The effects of acutely-administered morphine on mitogen stimulated lymphocyte proliferation and natural killer cell cytolytic activity were investigated. Two hours after a subcutaneous injection of morphine (25 mg/kg), blood lymphocyte proliferation was found to be 70% depressed, compared to saline-injected controls. This effect was partially antagonized in(More)
The period of transition from mandated school services with expectations for parental involvement to the often bewildering world of adult services can seem fraught with risk for families of young adults with developmental disabilities. Parental control and involvement is expected to diminish during this period when reality suggests a greater reliance on(More)
This article describes the development of a microcomputer-based videodisc assessment prototype for measuring children's social skills. The theoretical and empirical foundations for the content are described, and the contributions of interactive microcomputer-based video technology to assessment of children with handicaps are detailed. An application of(More)
Ratings on the acceptability, intrusiveness, restrictiveness, and efficacy of 18 commonly used interventions for decelerating behaviors were obtained from 58 special educators of students with severe handicaps. Results indicated that consensually high and low mean ratings were obtained for restrictiveness, intrusiveness, and acceptability. Ratings of(More)
The Social and Prevocational Information Battery, a series of knowledge tests developed for use with mildly retarded adolescents, was revised to facilitate assessment of moderately retarded persons knowledge in social and prevocational areas. In addition, the relationship between knowledge and applied performance in these domains was examined. Results(More)
Most measures of adaptive behavior are derived from rating scales. There are only a few instruments that approach the measurement of adaptive behavior through direct testing. In the present study we examined the relative efficacy of rating and testing approaches for predicting criterion behavior. Three tests from the Social and Prevocational Information(More)
The purpose of this study was to develop and standardize an instrument designed to assess the extent to which people with mental retardation demonstrate knowledge about citizenship rights and responsibilities. The test development phase included: (a) generating 83 items related to six content areas (i.e., human, civil, and legal rights; and moral, civic,(More)
Recurring amino acids sequence patterns are referred to as protein sequence motifs. The recurring patterns are so important because the conserved regions have the potential to reveal the role of the protein itself. In this paper, we modify the FGK model and apply the Hybrid Hierarchical K-means (HHK) clustering algorithm, which is a hybrid combination of(More)