Luiz Guilherme Darrigo Júnior

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CONTEXT Neurofibromatosis type 1 (NF-1) is the most prevalent autosomal dominant genetic disorder among humans. Moyamoya disease is a cerebral vasculopathy that is only rarely observed in association with NF-1, particularly in the pediatric age range. The present study reports an occurrence of this association in an infant. CASE REPORT An eight-month-old(More)
Type 1 neurofibromatosis (NF-1) is a multisystem genetic disease with significant cutaneous manifestations such as café-au-lait spots, freckles and neurofibromas. The incidence of NF-1 is about 1 : 2 500 new births; it affects equally all races and both sexes. Estimates show that there are currently in Brazil about 80 000 cases; worldwide, there are about(More)
Fever, skin rash, headache, and thrombocytopenia are considered hallmarks of dengue infection. However, these symptoms are frequently observed in infectious and non-infectious complications of hematopoietic stem cell transplant recipients and oncohematological patients. Thus, laboratory confirmation of dengue is relevant for prompt intervention and proper(More)
Part 1 of this guideline addressed the differential diagnosis of the neurofibromatoses (NF): neurofibromatosis type 1 (NF1), neurofibromatosis type 2 (NF2) and schwannomatosis (SCH). NF shares some features such as the genetic origin of the neural tumors and cutaneous manifestations, and affects nearly 80 thousand Brazilians. Increasing scientific knowledge(More)
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