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BACKGROUND Disturbed folate metabolism is associated with an increased risk of some cancers. Our objective was to determine whether blood levels of folate, vitamin B(12), and related metabolites were(More)
Folate-pathway gene polymorphisms have been implicated in several cancers and investigated inconclusively in relation to prostate cancer. We conducted a systematic review, which identified nine(More)
AIMS To explore the causal effect of long-term alcohol consumption on coronary heart disease risk factors. METHODS AND RESULTS We used variants in ADH1B and ADH1C genes as instrumental variables(More)