Luisa DeGiorgi

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Pre-immunization of BALB/c (H-2d) mothers with C57BL/10 (H-2b) or CBA/H (H-2k) spleen cells partially protected the F1 hybrid offspring of (BALB/c x C57BL/10) or (BALB/c x CBA/H) matings from graft-versus-host-disease (GVHD) induced by neonatal intraperitoneal inoculation with spleen cells of the paternal strain. The effects achieved were manifest as a(More)
Alloimmunization of BALB/c (H-2d) female mice with allogeneic spleen cells from C57BL/6 (H-2b) or CBA/H (H-2k) mice protects BALB/c offspring from graft-versus-host disease (GVH-D) following neonatal intraperitoneal inoculation of high doses of spleen cells respectively of C57BL/6 or CBA/H strains of mice. The mice survived GVH-D over one year after the(More)
In this report we describe a new diallelic gene system, Arp aand Arp b, which codes for surface antigens on murine lymphocytes. Arp bis present only in a mutant strain of BALB/c which is designated BALB/c-Arp b. Normal BALB/c and all other strains of mice tested express Arp a. The Arp bmutation is associated with a newly discovered polymorphism of the(More)