Learn More
The aim of this study was to investigate methods for detecting QTL in outbred commercial pig populations. Several QTL for back fat and growth rate, previously detected in experimental resource populations, were examined for segregation in 10 different populations. Two hundred trait-by-population-by-chromosome tests were performed, resulting in 20 tests(More)
An experimental F2 cross between Iberian and Landrace pig strains was performed to map quantitative trait loci (QTL) for diverse productive traits. Here we report results for meat quality traits from 369 F2 animals with records for pH 24 h postmortem (pH 24 h), muscle color Minolta measurements L* (lightness), a* (redness), and b* (yellowness), H* (hue(More)
Genomic evaluation models can fit additive and dominant SNP effects. Under quantitative genetics theory, additive or "breeding" values of individuals are generated by substitution effects, which involve both "biological" additive and dominant effects of the markers. Dominance deviations include only a portion of the biological dominant effects of the(More)
A method based on the analysis of recursive multiple-trait models was used to 1) estimate genetic and phenotypic relationships of calving ease (CE) with fertility traits and 2) analyze whether dystocia negatively affects reproductive performance in the next reproductive cycle. Data were collected from 1995 through 2002, and contained 33,532 records of CE(More)
The leptin receptor gene (LEPR) is a candidate for traits related to growth and body composition, and is located on SSC6 in a region where fatness and meat composition quantitative trait loci (QTL) have previously been detected in several F2 experimental designs. The aims of this work were: (i) to fine map these QTL on a larger sample of animals and(More)
The aim of this study was to investigate chromosomal regions affecting the number of teats in pigs and possible epistatic interactions between the identified quantitative trait loci (QTL). An experimental F2 cross between Iberian and Chinese Meishan lines was used for this purpose. A genomic scan was conducted with 117 markers covering the 18 porcine(More)
Variance components were estimated for litter size in Rasa Aragonesa sheep, a meat breed from northern Spain, to determine whether selective breeding for litter size is a reasonable strategy to improve reproductive performance. We assumed an animal mixed effect threshold model with a binary response variable. Marginal estimates of the genetic parameters(More)
We develop a mixed-model approach for QTL analysis in crosses between outbred lines that allows for QTL segregation within lines as well as for differences in mean QTL effects between lines. We also propose a method called "segment mapping" that is based in partitioning the genome in a series of segments. The expected change in mean according to percentage(More)
REASONS FOR PERFORMING STUDY Mesenchymal stromal cells (MSCs) represent an attractive source for regenerative medicine. However, prior to their application, fundamental questions regarding molecular characterisation, growth and differentiation of MSCs must be resolved. OBJECTIVES To compare and better understand the behaviour of equine MSCs obtained from(More)
This work presents an analysis of heterogeneity of environmental variance for slaughter weight (175 days) in pigs. This heterogeneity is associated with systematic and additive genetic effects. The model also postulates the presence of additive genetic effects affecting the mean and environmental variance. The study reveals the presence of genetic variation(More)