Luis Paulo da Silva Barra

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The objective of this study was to investigate the efficacy and safety of adjunctive lanicemine (NMDA channel blocker) in the treatment of major depressive disorder (MDD) over 12 weeks. This phase IIb, randomized, parallel-arm, double-blind, placebo-controlled study was conducted at 49 centers in four countries between December 2011 and August 2013 in 302(More)
This paper treats the problem of identifying a single inclusion in a conductor domain based on the knowledge of measured electrical potentials on the external boundary of the conductor body due to known injected electrical currents. The inclusion boundary is approximated by an Extended X-Spline, that allows identify inclusions with smooth or sharp boundary.(More)
In this work we present a parallel method for the solution of the inverse problem associated to Electrical Impedance Tomography (EIT). This technique tries to recover the spatial distribution of electrical conductivity in the interior of a body from electric potential measurements taken on the external boundary of the body. The problem we address in this(More)
This paper discusses shape optimization problems for elastic shafts under torsion using genetic algorithms (GA) coupled to the boundary element method (BEM). A GA is proposed to evolve the shape optimization involving the objective function that minimizes the area of the cross-section where the constraint imposed is a minimum value of torsional stiffness.(More)
Increasing attention has been focused on team management as a better way to improve software production. Nevertheless, most of the experiences described in recent publications to support the present trends in software engineering, deal mainly with large installations and -apparently- large human groups involved in systems development. The implementation of(More)
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