Luis Martinez

Shehla Pervin3
Gautam Chaudhuri3
Melissa Braga2
3Shehla Pervin
3Gautam Chaudhuri
2Melissa Braga
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There are two recognised modes of firing activity in thalamic cells, burst and tonic. A low-threshold (LT) burst (referred to from now on as 'burst') comprises a small number of high-frequency action potentials riding the peak of a LT Ca(2+) spike which is preceded by a silent hyperpolarised state > 50 ms. This is traditionally viewed as a sleep-like(More)
— This paper presents Tiji, a trajectory generation scheme, ie an algorithm that computes a feasible trajectory between a start and a goal state, for a given robotic system. Tiji is geared towards complex dynamic systems subject to differential constraints, such as wheeled vehicles, and its efficiency warrants it can be used in real-time. Above all, Tiji is(More)
A common shortcoming of many network measurement programs is that their metrics are not expressed in terms directly applicable to applications and users. To address this problem, we have developed the IP Benchmark (IPB), a benchmark program that synthetically generates traffic to simulate the network activity of common Internet applications. It measures the(More)
Schizophrenia is a psychotic illness characterized by problems in perception, learning, and memory. Post-mortem clinical data revealed abnormalities in neuronal organization, reduced soma and dendritic tree size. In rodents, reduction of glutamatergic neurotransmission by NMDA receptor antagonists mimics symptoms of schizophrenia. However, the dosage,(More)
We have previously reported arginase expression in human breast cancer cells and demonstrated that the inhibition of arginase by N(ω) hydroxy L-arginine (NOHA) in MDA-MB-468 cells induces apoptosis. However, arginase expression and its possible molecular targets in human breast tumor samples and potential clinical implications have not been fully(More)
Colloidal quantum dots have emerged as a material platform for low-cost high-performance optoelectronics. At the heart of optoelectronic devices lies the formation of a junction, which requires the intimate contact of n-type and p-type semiconductors. Doping in bulk semiconductors has been largely deployed for many decades, yet electronically active doping(More)
  • Michael Samis, P Eng, Luis Martinez, Principal, Manager, Graham A Davis +3 others
  • 2012
1 The statements made and opinions expressed in this paper are those of the author and do not represent an official position of Ernst and Young LLP. 2 The statements and views contained within this paper are those of the author in his private capacity and should not be taken to represent an official view of the Ontario Securities Commission, the Commission(More)
Breast cancer is a complex heterogeneous disease where many distinct subtypes are found. Younger African American (AA) women often present themselves with aggressive form of breast cancer with unique biology which is very difficult to treat. Better understanding the biology of AA breast tumors could lead to development of effective treatment strategies. Our(More)
Anticipated synchronization (AS) is an anti-intuitive phenomenon that can occur in two coupled dynamical systems when there is a dominant connectivity between the elements. AS occurs when a dynamical system A dominantly connects to another system B and B synchronously pulses before A does. It has been recently shown [1,2] that AS can occur in a model of(More)