Luis Javier Gonzalez

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Neuropeptide Y, a 36 amino acid peptide abundantly expressed in the brain, is the most potent orexigenic factor known to date in mammals. It has been shown to be one of the most conserved neuropeptides in vertebrate evolution. It seems that neuropeptide Y functions, in addition to sequence conservation, are also well conserved in fish. In the present study,(More)
The web application Isotopica has been developed as an aid to the interpretation of ions that contain naturally occurring isotopes in a mass spectrum. It allows the calculation of mass values and isotopic distributions based on molecular formulas, peptides/proteins, DNA/RNA, carbohydrate sequences or combinations thereof. In addition, Isotopica takes(More)
The four serotypes of dengue virus (DENV1-4) are the causal agents of the emerging disease Dengue Fever and its severe forms. DENV is inoculated into human blood through a mosquito bite. Thus, plasma is an important media for DENV dissemination in infected persons and several important interactions should take place for the virus with human plasma proteins(More)
Growth hormone secretagogues (GHS) such as ghrelin induce an array of effects in different types of organisms. The role of ghrelin in immune cell activation includes the release of pro-and anti-inflammatory cytokines via different signaling pathways [1,2]. For example, murine RAW 264.7 macrophages express both ghrelin and GHS receptors. Treatment of these(More)
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