Luis García-Ortiz

Cristina Agudo-Conde7
Carlos Martínez-Salgado6
7Cristina Agudo-Conde
6Carlos Martínez-Salgado
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BACKGROUND Endoglin is involved in the regulation of endothelial function, but there are no studies concerning its relation with hypertension- and diabetes-associated pathologies. Thus, we studied the relationship between plasma levels of soluble endoglin and cardiovascular alterations associated with hypertension and diabetes. METHODS We analyzed 288(More)
The scope of this work is to develop a technological platform specialized in assessing retinal vessel caliber and describing the relationship of the results obtained to cardiovascular risk. Population studies conducted have found retinal vessel caliber to be related to the risk of hypertension, left ventricular hypertrophy, metabolic syndrome, stroke, and(More)
  • Emiliano Rodríguez-Sánchez, Sara Mora-Simón, María C Patino-Alonso, Ricardo García-García, Alfonso Escribano-Hernández, Luis García-Ortiz +2 others
  • 2011
BACKGROUND Few data are available on the prevalence of cognitive impairment (CI) in Spain, and the existing information shows important variations depending on the geographical setting and the methodology employed. The aim of this study was to determine the prevalence of CI in individuals aged over 65 in an urban area, and to analyze its associated risk(More)
BACKGROUND No comparisons have been made of scales estimating cardiovascular mortality and overall cardiovascular morbidity and mortality. The study objectives were to assess the agreement between the Framingham-D'Agostino cardiovascular risk (CVR) scale and the chart currently recommended in Europe (SCORE) with regard to identification of patients with(More)
  • Manuel A. Gomez-Marcos, José I. Recio-Rodríguez, Maria C. Patino-Alonso, Vicente Martinez-Vizcaino, Carme Martin-Borras, Aventina de-la-Cal-dela-Fuente +4 others
  • 2014
OBJECTIVE To analyze the relationship between regular physical activity, as assessed by accelerometer and 7-day physical activity recall (PAR), and plasma fibrinogen concentrations. METHODS A cross-sectional study in a previously established cohort of healthy subjects was performed. This study analyzed 1284 subjects who were included in the EVIDENT study(More)
BACKGROUND We investigated the association between heart rate and its variability with the parameters that assess vascular, renal and cardiac target organ damage. METHODS A cross-sectional study was performed including a consecutive sample of 360 hypertensive patients without heart rate lowering drugs (aged 56 ± 11 years, 64.2% male). Heart rate (HR) and(More)
Oxidative stress is associated with cardiac and vascular defects leading to hypertension and atherosclerosis, being superoxide dismutase (SOD) one of the main intracellular antioxidant defence mechanisms. Although several parameters of vascular function and structure have a predictive value for cardiovascular morbidity-mortality in hypertensive patients,(More)
  • Manuel A Gomez-Marcos, Carlos Martinez-Salgado, Rogelio Gonzalez-Sarmiento, Jesus Ma Hernandez-Rivas, Pedro L Sanchez-Fernandez, Jose I Recio-Rodriguez +17 others
  • 2016
INTRODUCTION The process of population ageing that is occurring in developed societies represents a major challenge for the health system. The aim of this study is to analyse factors that have an influence on early vascular ageing (EVA), estimated by carotid-femoral pulse wave velocity (cf-PWV) and Cardio Ankle Vascular Index (CAVI), and to determine(More)
BACKGROUND There is limited evidence concerning the relationship between vascular disease and health-related quality of life (HRQL). We investigated the relationship between vascular structure and function with health-related quality of life in a population with intermediate cardiovascular risk. METHODS This study analyzed 303 subjects with ankle-brachial(More)
BACKGROUND We analyzed the associations between diabetes and cognitive impairment (CI) and dependence in a population of patients 65 years or older. METHODS Cross-sectional study. We randomly selected 311 participants over the age of 65 living in an urban area of Spain. The mean age of the cohort was 75.89 ± 7.12 years, and 69 of the individuals (22.2%)(More)