Luis F. Miranda

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In the present study, we show a biphasic activation of hypoxia inducible factor 1alpha (HIF-1) after stroke that lasts for up to 10 d, suggesting the involvement of the HIF pathway in several aspects of the pathophysiology of cerebral ischemia. We provide evidence that HIF-1-mediated responses have an overall beneficial role in the ischemic brain as(More)
The objective of this study was to assess whether clinical measures of rheumatoid arthritis activity and severity were influenced by tumor necrosis factor-alpha (TNF-alpha) promoter genotype/haplotype markers. Each patient's disease activity was assessed by the disease activity score using 28 joint counts (DAS28) and functional capacity by the Health(More)
Acoustic support on auditorium stages is conventionally quantified using the stage support parameters (e.g., ISO3382-1). These parameters are derived from room impulse responses measured between an omnidirectional source and receiver. For early stage support (ST Early), the source and receiver are horizontally separated by 1 m, and the degree of support is(More)
Strawberry is a high value crop worth 315.6 million euros in 2013 in Spain. Strawberry diseases are commonly controlled by soil fumigation with toxic chemicals. However, since 2007, the methyl bromide fumigant is banned for strawberry cultivation. Moreover, European policies are progressively restricting the use of other toxic fumigants such as(More)
We present Very Large Array (VLA) observations of H 2 O and OH masers, as well as radio continuum emission at 1.3 and 18 cm toward three sources previously cataloged as planetary nebulae (PNe) and in which single-dish detections of H 2 O masers have been reported: IRAS 17443−2949, IRAS 17580−3111, and IRAS 18061−2505. Our goal was to unambiguously confirm(More)
I hereby declare that I am the sole author of this thesis. This is a true copy of the thesis, including any required final revisions, as accepted by my examiners. I understand that my thesis may be made electronically available to the public. Abstract The objective of the present study was to develop a fluid flow-coupled distinct element model capable of(More)
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