Luis Cláudio Lemos Correia

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Heart valve prosthesis unquestionably improve quality of life and survival of patients with severe valvular heart disease, but the need for antithrombotic therapy to prevent thromboembolic complications is a major challenge to clinicians and their patients. Of the articles analyzed, most were retrospective series of cases or historical cohorts obtained from(More)
BACKGROUND An adequate door-to-balloon time (<120 minutes) is the necessary condition for the efficacy of primary angioplasty in infarction to translate into effectiveness. OBJECTIVE To describe the effectiveness of a quality of care protocol in reducing the door-to-balloon time. METHODS Between May 2010 and August 2012, all individuals undergoing(More)
In the first semester of this year, the U.S. Food and Drug Administration (FDA) approved a new drug for the treatment of heart failure, LCZ696, commercially known as Entresto. This new treatment option was evaluated by the FDA on a priority basis (fast track designation), which allowed a faster release than usual. In Brazil, the drug is being evaluated by(More)
BACKGROUND The ACUITY and CRUSADE scores are validated models for prediction of major bleeding events in acute coronary syndrome (ACS). However, the comparative performances of these scores are not known. OBJECTIVE To compare the accuracy of ACUITY and CRUSADE in predicting major bleeding events during ACS. METHODS This study included 519 patients(More)
BACKGROUND The incremental prognostic value of plasma levels of C-reactive protein (CRP) in relation to GRACE score has not been established in patients with acute coronary syndrome (ACS) with non-ST segment elevation. OBJECTIVE To test the hypothesis that CRP measurements at admission increases the prognostic value of GRACE score in patients with ACS. (More)
BACKGROUND The TIMI Score for ST-segment elevation myocardial infarction (STEMI) was created and validated specifically for this clinical scenario, while the GRACE score is generic to any type of acute coronary syndrome. OBJECTIVE Between TIMI and GRACE scores, identify the one of better prognostic performance in patients with STEMI. METHODS We included(More)
Besides providing diagnostic or prognostic accuracy, a biomarker must be effective to ensure its adequate use in routine clinical implementation. Effectiveness can be defined as an individual's potential to benefit from using the biomarker. This benefit includes the prevention of undesirable clinical outcomes and improvement in an individual's quality of(More)
In stable coronary artery disease, the indication for revascularization procedures based on the anatomical detection of stenotic coronary lesions, regardless of clinical findings, has been called 'oculostenotic reflex'. That expression was ironically created by Topol E. and Nissen S., and aimed at warning about the fact that not every obstruction has to be(More)
Pereira MP, et al. Correlation of risk scores with coronary anatomy in non-ST-elevation acute coronary syndrome. References Reply When Santos et al 1 have concluded that risk scores correlate with coronary anatomy, they considered all analyses performed: statistical correlation analysis with the non-parametric Spearman test 2 and the predictive ability of(More)
Introduction. The RIFLE classification defines three severity criteria for acute kidney injury (AKI): risk, injury, and failure. It was associated with mortality according to the gradation of AKI severity. However, it is not known if the APACHE II score, associated with the RIFLE classification, results in greater discriminatory power in relation to(More)
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