Learn More
Power management has been increasingly critical for sustainable data centers. One particular aspect that has a strong impact on the power consumed by a data center is how the workload is distributed among its servers. This distribution can be done integrating thermal models that allow balancing cooling needs with computing needs contributing to reduce(More)
OBJECTIVE To evaluate the long-term safety, tolerability and efficacy of once-daily eslicarbazepine acetate (ESL) as adjunctive therapy in adults with partial-onset seizures. METHODS One-year open-label extension (OLE) study with ESL in patients who completed a randomised, double-blind placebo-controlled trial (study BIA-2093-302; Epilepsy Res. 89 (2010)(More)
OBJECTIVE To evaluate the pharmacokinetics of eslicarbazepine acetate (ESL) at steady-state in adults with partial-onset seizures who have taken ESL for at least 1 year with one or two concomitant antiepileptic drugs (AEDs). METHODS Blood samples for the pharmacokinetic assessment were taken at pre-dose, and 1, 2, 3, 4, 6, 8, 12 and 24h post-dose at(More)
Segments are fundamental units in animal development which are made of distinct cell lineages separated by boundaries. Although boundaries show limited plasticity during their formation for sharpening, cell lineages make compartments that become tightly restricted as development goes on. Here, we characterize a unique case of breaking of the segment(More)
This paper presents the EURESCOM 1 project MUST, (MUltimodal, multilingual information Services for small mobile Terminals). The project started in Febru-ary 2001 and will last till the end of 2002. Based on existing technologies and platforms a multimodal demonstrator (the MUST tourist guide to Paris) has been implemented. This demonstrator uses speech and(More)
Epithelial wound healing relies on tissue movements and cell shape changes. Our work shows that, immediately after wounding, there was a dramatic cytoskeleton remodeling consisting of a pulse of actomyosin filaments that assembled in cells around the wound edge and flowed from cell to cell toward the margin of the wound. We show that this actomyosin flow(More)
OBJECTIVE To investigate the efficacy and safety of once-daily eslicarbazepine acetate (ESL) when used as add-on treatment in adults with > or = 4 partial-onset seizures per 4-week despite treatment with 1 to 3 antiepileptic drugs (AEDs). METHODS This double-blind, parallel-group, multicenter study consisted of an 8-week observational baseline period,(More)
OBJECTIVES To evaluate the efficacy and safety of eslicarbazepine acetate (ESL) as adjunctive therapy in adults with partial-onset seizures. MATERIAL AND METHODS Double-blind, placebo-controlled, parallel-group, multicenter study consisting of an 8-week baseline period, after which patients were randomized to placebo (n = 87) or once-daily ESL 800 mg (n =(More)