Luis Almeida Costa

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The trypanosomatid flagellar apparatus contains conventional and unique features, whose roles in infectivity are still enigmatic. Although the flagellum and the flagellar pocket are critical organelles responsible for all vesicular trafficking between the cytoplasm and cell surface, still very little is known about their roles in pathogenesis and how(More)
Building on the growing literature that views organizations as complex adaptive systems, this paper proposes a general model to analyze the relationship between organizational context and attitudes. In particular, we focus on how the system of formal and informal communication channels that characterize an organization and the timing of information flows(More)
In this paper the authors update on the deletereous or beneficial roles of human and animal secretory phospholipases A2 (sPLA2). Although human sPLA2-IIA (inflammatory) was initially thought as a foe because its pathogenic implication in sepsis, multiorganic failure or other related syndromes, recent data indicates its role in in the antiinfectious host(More)
VRCTC-310-ONCO, an agent based on the snake phospholipase A2 (crotoxin), is currently under clinical development. After phase I study in patients by intramuscular administration, the interest of intravenous (IV) dosing arose. To evaluate IV administration of VRCTC-310-ONCO in rabbits, ten animals were subjected to surgical implant of fixed jugular catheter,(More)
OBJECTIVE To determine medication errors in a public and in a private hospital. METHOD Cross-sectional. 638 dosis opportunities for errors (administered dosis + omitted dosis) were assessed in January, 2005. Medication error was defined as any given dose different from a legible prescription on patient chart. The error rate was calculated by the following(More)
The alignment of collective goals and individual behavior has been extensively studied by economists under a principal-agent framework. Two main solutions have been presented: explicit incentive contracts and monitoring. These solutions correspond to changes in the objective situation faced by individuals. However, an extensive literature in social(More)
OBJECTIVE To outline passive information offered by the Drug Information Center (DIC) of the Federal University of Bahia College of Pharmacy. METHODOLOGY Descriptive and prospective study of requests received at the DIC from March, 1997 to December, 2003. Results, represented as frequencies, were obtained by using Microsoft Excel. RESULTS 1,267 requests(More)
This paper studies …rms'decisions to form partnerships to develop new projects and the reputation implications of such decisions. Speci…cally, we analyze how …rms'qualities, initial reputations and participation levels a¤ect the evolution of …rms'reputations and incentives to form partnerships. We consider both the case where participation levels are(More)
OBJECTIVE The purpose of this study is to assess the relationship of the upper and lower arch dimension changes after the rapid maxillary expansion (RME) with the screw opening of the modified Hyrax® type appliance. MATERIALS AND METHODS Initial (T1) and final (T2) models of study of 63 children between 7 years and 6 months and 16 years and 5 months were(More)
OBJECTIVE To describe a pharmacist s field of activity in drug-related clinical trials. METHOD A non-systematic assessment of available scientific literature in international databases queried during the period of May 05 to 31, 2005. RESULTS In all, 36 papers were obtained regarding the role of hospital pharmacists in the development of drug-related(More)
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