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BACKGROUND Meningococcal C (MenC) conjugate vaccines have controlled invasive diseases associated with this serogroup in countries where they are included in National Immunization Programs and also in an extensive catch-up program involving subjects up to 20 years of age. Catch-up was important, not only because it prevented disease in adolescents and young(More)
Random networks are emerging in epidemiology as a way of simulating more realistic random contact behaviours. A network is a set of nodes representing individuals. Labels or properties may be assigned to each node, for instance, age, sex, state respect to disease (susceptibility, infection, recovery, etc.). Nodes are connected by ties that represent disease(More)
We propose an age-structured mathematical model for respiratory syncytial virus in which children aged <1 year are especially considered. Real data on hospitalized children in the Spanish region of Valencia were used in order to determine some seasonal parameters of the model. Weekly predictions of the number of children aged <1 year that will be(More)
It is the aim of this paper to investigate a suitable approach to compute solutions of the powerful Michaelis-Menten enzyme reaction equation with less computational effort. We obtain analytical-numerical solutions using piecewise finite series by means of the differential transformation method, DTM. In addition, we compute a global analytical solution by a(More)
In 2008, a team of astronomers reported an anomalous retrograde precession of the perihelion of Saturn amounting to ∆ω̇SATURN = −0.006(2) arcsec per century (arcsec cy−1). This unexplained precession was obtained after taking into account all classical and relativistic effects in the context of the highly refined EPM2008 ephemerides. More recent analyzes(More)