Luigi Toniolo

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During ageing skeletal muscles undergo a process of structural and functional remodelling that leads to sarcopenia, a syndrome characterized by loss of muscle mass and force and a major cause of physical frailty. To determine the causes of sarcopenia and identify potential targets for interventions aimed at mitigating ageing-dependent muscle wasting, we(More)
Polyketone polymer -[-CO-CH(2)-CH(2)-](n)-, obtained by copolymerization of ethene and carbon monoxide, is utilized for immobilization of three different enzymes, one peroxidase from horseradish (HRP) and two amine oxidases, from bovine serum (BSAO) and lentil seedlings (LSAO). The easy immobilization procedure is carried out in diluted buffer, at pH 7.0(More)
Nitrocellulose is one of the most commonly used compounds in ammunition and paint industries and its recalcitrance to degradation has a negative impact on human health and the environment. In this study the capability of Desulfovibrio desulfuricans ATCC 13541 to degrade nitrocellulose as binder in paint was assayed for the first time. Nitrocellulose-based(More)
Phenotypic expression of 2b myosin heavy chain isoform: a comparative study among species and different muscles F. Mascarello & M. Patruno & L. Toniolo & C. Reggiani & L. Maccatrozzo Published online: 4 July 2009 # Springer Science + Business Media B.V. 2009
Sarcomeric myosin is characterised by a high structural heterogeneity which is essential to achieve different functional performances. This variability is based on the presence of different myosin heavy chain isoforms (MHC) which are considered to be the marker of fibre types. Different genes that codify for type 1, 2A, 2X and 2B myosin heavy chain isoforms(More)
The complex trans -[Pd(COOCH3)(H2O)(PPh3)2](TsO) (I) has been synthesized by reacting trans -[Pd(COOCH3)Cl(PPh3)2] with AgTsO in methanol. It has been characterized by IR, H and P NMR spectroscopy. Crystals of trans [Pd(COOCH3)(H2O)(PPh3)2](TsO) /(CH3OH) (II) have been obtained by re-crystallization of I in methanol. The structure of the complex has been(More)
The photobiological activity of a series of psoralen isosters carrying a nitrogen atom at 8 position, new potential drugs for the photochemotherapy of hyperproliferative skin diseases, have been studied; the more active derivatives appeared to be 5,4'-dimethyl-8-azapsoralen and 3,4,4'-trimethyl-8-azapsoralen which induced a strong inhibition of DNA(More)
cis-[Pd(ONO(2))(2)(PPh(3))(2)] (1) reacts under mild conditions with CO in methanol (MeOH) in the presence of pyridine (py), yielding trans-[Pd(COOMe)(ONO(2))(PPh(3))(2)] (1a). The use of NEt(3) instead of py leads to a mixture of 1a, trans-[Pd(COOMe)(2)(PPh(3))(2)] (2), and [Pd(CO)(PPh(3))(3)]. Pure 2 was prepared by reacting cis-[Pd(OTs)(2)(PPh(3))(2)](More)
Certain 2-substituted 1H-pyrrolo [3,2-h] quinolines have been prepared and their biological activity in mammalian cells and in some microorganisms have been studied. These compounds represent a simplified ellipticine heterocyclic moiety: in addition they have a different ring condensation, leading to an angular molecular structure instead of a linear one.(More)
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