Luigi Grasso

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Novel technologies are being developed to improve patient therapy through the identification of targets and surrogate molecular signatures that can help direct appropriate treatment regimens for efficacy and drug safety. This is particularly the case in oncology whereby patient tumor and biofluids are routinely isolated and analyzed for genetic,(More)
BACKGROUND Staphylococcal enterotoxins are considered potential biowarfare agents that can be spread through ingestion or inhalation. Staphylococcal enterotoxin B (SEB) is a widely studied superantigen that can directly stimulate T-cells to release a massive amount of proinflammatory cytokines by bridging the MHC II molecules on an antigen presenting cell(More)
Over-expression of endosialin/CD248 (herein referred to as CD248) has been associated with increased tumor microvasculature in various tissue origins which makes it an attractive anti-angiogenic target. In an effort to target CD248, we have generated a human CD248 knock-in mouse line and MORAb-004, the humanized version of the mouse anti-human CD248(More)
This paper introduces an open, interoperable and cloud computing-based citizen engagement platform for the management of administrative processes of public administrations, which also increases the engagement of citizens. The citizen engagement platform is the outcome of a three-year Italian national project called PRISMA (Interoperable cloud platforms for(More)
The exponential increment in the production of biomedical data is forcing a higher level of automatization to analyze it. Therefore , biomedical researchers have to entrust bioinformaticians to develop software able to process a huge amount of data on high performance unix-based servers. However, most of the software is developed with a very basic,(More)
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