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Low frequency and intensity ultrasound (LFU) sonication can selectively induce brain tumor cell apoptosis without damaging neural cells, while also enhancing drug delivery to brain tumors. To explore the underlying mechanisms of related pathways in LFU-induced apoptosis, we investigated the expression of proteins associated with LFU-induced apoptosis. C6(More)
BACKGROUND/AIMS Sorafenib has been proved to prolong survival of patients with advanced hepatocellular carcinoma (HCC), but with moderate efficacy. The present study aimed to evaluate the prognostic factors for overall survival (OS) in Chinese patients with advanced HCC treated with sorafenib who had been refractory to transarterial chemoembolization (TACE)(More)
In this paper, a boundary-conformed tool path generation method for either compound or trimmed surfaces are proposed, based on two powerful reparametrization schemes- the discretized harmonic mapping and the convex combination mapping. By globally mapping a 3D surface onto a 2D unit square and then planning an iso-parametric curve in the 2D domain, the(More)
Glial cells are important components of the nervous system. However, how they respond to physiological stimuli in vivo remains largely unknown. In this study, we investigated the electrophysiological activities and Ca2+ responses of the C. elegans amphid sheath glia (AMsh glia) to tactile stimulation in vivo. We recorded robust inward currents and Ca2+(More)
The Bohai Sea (BS) and Yellow Sea (YS), which are adjacent to the most urbanized and industrialized areas in China, are facing a variety of environmental problems. Two cruises were conducted to investigate the pollution status of toxic metals in BS and YS sediments. They generally presented a decreasing trend from near shore to offshore. In addition, two(More)
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