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- Publications
- Influence
Investigation of the membrane localization and distribution of flavonoids by high-resolution magic angle spinning NMR spectroscopy.
- H. Scheidt, A. Pampel, Ludwig Nissler, R. Gebhardt, D. Huster
- Chemistry, Medicine
- Biochimica et biophysica acta
- 27 May 2004
To investigate the structural basis for the antioxidative effects of plant flavonoids on the lipid molecules of cellular membranes, we have studied the location and distribution of five different… Expand
Flavonoid binding to a multi-drug-resistance transporter protein: an STD-NMR study
- Ludwig Nissler, R. Gebhardt, S. Berger
- Chemistry, Medicine
- Analytical and bioanalytical chemistry
- 7 July 2004
Flavonoids are well known to inhibit the function of the multi-drug-resistance (mdr) transporter by interacting with their ATP binding domains. The precise orientation of these molecules inside the… Expand
Synthesis and biological evaluation of new derivatives of emodin.
- Lars Teich, K. S. Daub, Vera Krügel, Ludwig Nissler, R. Gebhardt, K. Eger
- Chemistry, Medicine
- Bioorganic & medicinal chemistry
- 15 November 2004
Drugs containing an anthraquinone moiety such as daunorubicin (Daunoblastin) and mitoxantrone (Onkotrone) constitute some of the most powerful cytostatics. They suppress tumor growth mainly by… Expand