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Interplay between proteins, nucleic acids, carbohydrates and/or lipids is involved in almost every process in life on earth. As a consequence, a wide range of diseases results from abnormal… (More)
An enantioselective three-step synthesis of the GABA uptake inhibitor (S)-(+)-homo-β-proline was developed. The basis for the synthesis was the enantioselective CuI-catalyzed cyclopropanation of… (More)
Cyclopropanated heterocycles have been shown to be invaluable building blocks for the synthesis of a broad variety of natural products and other biologically relevant compounds. The first part of the… (More)