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For the rapid and simple diagnosis of schistosomiasis, a reagent strip assay for detection of circulating cathodic antigen (CCA) in urine was developed. The test was based on a previously developed sandwich enzyme-linked immunosorbent assay (ELISA) using a combination of two anti-CCA monoclonal antibodies. For the reagent strip assay, as the capture matrix,(More)
We studied the fluctuations of schistosome circulating antigens in urine as compared with fecal egg counts in 60 Burundese individuals infected with Schistosoma mansoni. Levels of circulating anodic antigen (CAA) and circulating cathodic antigen (CCA) in the urine were determined by quantitative enzyme-linked immunosorbent assays. Fecal samples were(More)
BACKGROUND Ambient particulate matter and nanoparticles have been shown to translocate to the brain, and potentially influence the central nervous system. No data are available whether this may lead to functional changes in the brain. METHODS We exposed 10 human volunteers to dilute diesel exhaust (DE, 300 mug/m3) as a model for ambient PM exposure and(More)
This study was performed to investigate the effect of weight-training (12 wk; 21 male subjects) on energy expenditure and substrate utilization during sleep. Sleeping metabolic rate (SMR) as measured in a respiration chamber was calculated according to three procedures: the lowest mean energy expenditure of a shiftable 3-h interval between 0:00 and 6:00(More)
Solid phase assays for the measurement of functional antibody affinity are increasingly being used in both clinical and research settings. The majority of such assays employ a chemical reagent to disturb antibody binding but relatively little is known about the properties of such reagents and the basis of their effect on antigen-antibody binding. We have(More)
The purpose of this study was to examine the effect of an 18-wk weight-training program on average daily metabolic rate (ADMR). Before the intervention and in weeks 8 and 18 (T0, T8, and T18, respectively) data on body composition, sleeping metabolic rate (SMR), food intake, energy cost of the weight-training program (EEex), and nontraining physical(More)
A group of 31 school children from Gabon infected with Schistosoma haematobium was examined before praziquantel therapy and followed on days 3, 9, 14, 21, 24, 28, 31 and 35 after therapy. The day-to-day variation of schistosome circulating antigens, urinary egg output, and the reagent strip index (RSI, a pathologic marker) was studied in six consecutive(More)
The aim of the present study was to investigate whether weight-training-induced adaptations in body composition and isokinetic strength differ as a function of body build. Body build of a subject was characterized as the extent to which a person's fat-free mass index (FFMI = fat-free mass.height-2;kg.m-2) differs from the regression of FFMI over fat mass(More)
To quantify day-to-day variability in energy expenditure (EE) during weight-training, 10 male subjects completed 6 training sessions that consisted of a warming-up and cooling-down phase (10 min; arm cranking or cycling) and a computer-paced weight-training phase using standard weights (42 min; 10 exercises, 3 x 15 repetitions, work to rest ratio = 1:1).(More)