Ludmila I Kramarova

Learn More
To explain the distinctive pharmacological profiles observed for adrenergic stimulation of cell proliferation (␤ 1) and cell differentiation (␤ 3), the adrenergic control of cAMP accumulation was investigated during brown adipocyte development. In preadipocytes, norepineph-rine (NE) increased cAMP levels but the ␤ 3-agonists BRL-37344 and CGP-12177 did not;(More)
The ligand-binding characteristics (B(max) and K(D)) of alpha(1)- and beta(1)/beta(2)-adrenoceptors were investigated in membranes prepared from brown adipose tissue (BAT) of warm-acclimated, cold-acclimated, hibernating and arousing ground squirrels (Spermophillus undulatus) and hamsters (Mesocricetus auratus) by specific binding of [(3)H]prazosin and(More)
  • 1