Lucine Avakian

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It is well known that the disease progression in cystic fibrosis (CF) patients may be diverse in subjects with identical mutation in CFTR gene. It is quite possible that such heterogeneity is associated with TNF-α and/or LT-α gene polymorphisms since their products play a key role in inflammation. The aim of the study was to investigate the possible roles(More)
An electron microscopic investigation on ultrastructure of synapses and ventral horns of the lumbar thickening in the spinal cord of cats with parathyroprival tetany has been performed. When motor disorders are clearly seen on the 2d - 4th days after removal of the parathyroid glands, together with the changes demonstrating functional activity of the(More)
BACKGROUND Anti-inflammatory therapy is a logical approach to slowing the inevitable lung function deterioration in cystic fibrosis (CF) patients. This study's aim was to evaluate inflammatory markers and disease progression in paediatric CF patients chronically treated with azithromycin or low-dose prednisolone. METHODS The study included 204 patients(More)
Electron microscopic investigation of the adrenocortical fascicular zone was conducted to determine serum calcium content in control and parathyroprivic random bred adult rats on the 5th, 15th and 30th days after parathyroidectomy. During the entire experiment calcium content was lowered. There were no marked changes in the ultrastructure of the secretory(More)
By means of the light and electron microscopy methods efferent connections of the fields 5a, 5b and 7 with the caudate nucleus have been studied. These fields are predominantly projected to the dorsolateral corner of the middle and posterior head of the caudate nucleus. The fields 5b and 7, unlike the field 5a, give also origin to the fibers, terminating in(More)
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