Lucimara Gaziola de la Torre

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The greatest challenges in vaccine development include optimization of DNA vaccines for use in humans, creation of effective single-dose vaccines, development of delivery systems that do not involve live viruses, and the identification of effective new adjuvants. Herein, we describe a novel, simple technique for efficiently vaccinating mice against(More)
BACKGROUND Tuberculosis is a major threat to human health. The high disease burden remains unaffected and the appearance of extremely drug-resistant strains in different parts of the world argues in favor of the urgent need for a new effective vaccine. One of the promising candidates is heat-shock protein 65 when used as a genetic vaccine (DNAhsp65).(More)
Nowadays, many researchers in the field of gene delivery are focused on develop methods to produce nanoparticles with physicochemical characteristics in reproducible, continuous and scalable process without requiring post processing steps. Another key factor is to transpose conditions from in vivo gene delivery into cells and tissue to in vitro. In this(More)
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